Friday, April 10, 2026

The next big expansion at Cleveland Clinic’s Main Campus is in the works

The Cleveland Clinic InterContinental Hotel on Carnegie Avenue at East 100th Street may
be replaced with an inpatient hospital bed tower. But the hotel isn’t disappearing. It’s relo-
cating nearby. And it’s one of several major developments planned by the Clinic for its
Main Campus near University Circle (Google). CLICK IMAGES TO ENLARGE THEM.

By this time next year, after the Cleveland Clinic’s largest-ever building is due to open with 2,000 additional employees, there should be a lot more clarity that’s publicly available on Ohio’s largest employer’s next expansive plans for its Main Campus near Cleveland’s University Circle.

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